Skip to main content
⚠️ Research Notice: This information is for educational and laboratory research purposes only. Not for human consumption.
Other Family medium Confidence

P21

Last Updated: January 2025
Calculate P21 Decay

Key Takeaways: P21

P21 is a Other peptide primarily researched for:

  • Increased neurogenesis (New neurons)
  • Elevates BDNF levels
  • Reduces amyloid plaque formation

Research Profile

Stability Class Highly Volatile
Confidence medium
Freezable? ✅ Yes

P21 (or P021) is a synthetic analog of Ciliary Neurotrophic Factor (CNTF). It is specialized in “brain remodeling” and cognitive longevity.

Growing New Nerves

P21 works by boosting the levels of Brain-Derived Neurotrophic Factor (BDNF) and promoting the maturation of new neurons in the hippocampus. Unlike traditional stimulants, it supports long-term brain health by physically increasing the density of the neural network.

Alzheimer’s Defense

In research models, P21 has shown a remarkable ability to inhibit the formation of amyloid-beta and tau proteins—the harmful substances that drive Alzheimer’s disease. This makes it a primary focus for research into both cognitive enhancement and the prevention of brain aging.

Key Benefits

  • Increased neurogenesis (New neurons)
  • Elevates BDNF levels
  • Reduces amyloid plaque formation
  • Improves synaptic density

Potential Side Effects

  • Excellent safety profile
  • Rare fatigue

Stability Profile

Fridge (2-8°C)

Stable for 30 days

Room Temp

Relatively stable for 14 days