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Temperature Stability Calculator

Project potency decline at freezer, fridge, and room storage using peptide-specific decay rates.

Formula: P(t) = 100 × (1 − r)t — first-order discrete exponential decay, where r = daily decay rate and t = days. Peptide-specific rates are [Model Estimates — PeptideClock] calibrated to theICH Q1A(R2) pharmaceutical stability framework (Waterman & Adami, Int J Pharm 2005, PMID 15778049). Protein aggregation may be non-Arrhenius (Wang & Roberts, AAPS J 2013, PMID 23615748).

Potency decay by temperature

0%50%100%discard 50%day 0day 90
Freezer (−20°C) Fridge (2–8°C) Room (~25°C)

Projected Potency

DaysFreezer (-20°C)Fridge (2-8°C)Room (~25°C)
0100%100%100%
7100%97%70%
1499%93%49%
3099%86%21%
6097%74%5%
9096%64%1%