MOTS-c

MOTS-c is a 16-amino acid peptide encoded in the mitochondrial genome. It is often referred to as an “exercise mimetic” because of its profound effects on muscle metabolism and energy regulation.

Mitochondrial-Nuclear Signaling

MOTS-c is unique because it acts as a messenger between the mitochondria and the cell nucleus. It regulates the AMPK pathway, which helps cells manage glucose more effectively and boosts the breakdown of fatty acids for energy.

Research for Longevity

Natural levels of MOTS-c decline as we age. Research is currently focused on how replenishing this peptide can combat age-related metabolic decline, improve physical performance, and support a longer healthspan.