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Other Family medium Confidence

Humanin

Last Updated: January 2025
Calculate Humanin Decay

Key Takeaways: Humanin

Humanin is a Other peptide primarily researched for:

  • Protects cells from apoptosis
  • Enhanced insulin sensitivity
  • Neuroprotective (Alzheimer's research)

Research Profile

Stability Class Standard
Confidence medium
Freezable? ✅ Yes

Humanin is a mitochondrial-derived peptide (MDP) that acts as a cytoprotector, shielding cells from various forms of stress and programmed cell death (apoptosis).

Mitochondrial Sentinel

Humanin is one of the key signals our mitochondria use to communicate health status to the cell nucleus. Research indicates it can protect neurons from the toxicity associated with Alzheimer’s disease and help prevent the loss of cardiovascular cells under stress.

Metabolic Ally

Humanin has also shown the ability to improve glucose handling and insulin sensitivity in research models. As a compound and signaling molecule, it is a primary focus for studies investigating why some individuals age more “successfully” than others.

Key Benefits

  • Protects cells from apoptosis
  • Enhanced insulin sensitivity
  • Neuroprotective (Alzheimer's research)
  • Supports cardiovascular health

Potential Side Effects

  • Well-tolerated in animal studies

Stability Profile

Fridge (2-8°C)

Stable for ~28 days

Room Temp

Degrades rapidly at higher temps